Partner with Basepaws to advance feline health. Our approach combines animal health genetics and microbiome data with an extensive network of cats, cat parents, veterinarians and researchers.
Does your cat have a specific medical condition? Apply now to take part in our ongoing research studies!
If you are a cat parent who would like to contribute to advancing feline health research, we are excited to work with you! We are conducting studies by collecting cat DNA and oral microbiome samples, as well as health history data. Please review the list of research programs and required criteria. We require cat owners to submit records as part of the application process.
Chronic Kidney Disease (CKD)
Chronic kidney disease (CKD) is a serious health problem, affecting mostly older cats. If your cat is suffering from CKD and they were diagnosed before it turned 5 years old, your cat’s sample might be particularly useful for discovering genetic markers associated with CKD.
Diagnosis of CKD by a veterinarian.
Unrelated hyperthyroidism, UTI, systemic hypertension, hypoadrenocorticism, nephrolithiasis and ureterolithiasis.
Anecdotal evidence suggests that the oldest cat on record lived to be 35 years old! We believe that understanding genetic factors contributing to feline longevity can help us keep cats alive longer. If you have a cat aged 17 or older, they could be a perfect candidate for this study and for helping us understand biological markers associated with feline longevity.
Inclusion criteria: Age 17+
Exclusion criteria: Age <17
Dental Diseases (Periodontal Disease, Tooth Resorption, Stomatitis)
It is estimated that 50-90% of all cats older than 4 years suffer from some kind of dental disease. We developed the first-of-its-kind at-home feline dental health test assessing the cat’s risk of periodontal disease, tooth resorption, and bad breath based on the state of the oral microbiome. We were able to characterize the microbial profile associated with each of those three conditions. We are currently in active collaborations with veterinary clinics to further refine our knowledge about the microbial signature of periodontal disease and tooth resorption, as well as identify the microbial culprits of feline gingivostomatitis.
Feline gastrointestinal (GI) lymphoma is notoriously hard to diagnose and is often confused with Inflammatory Bowel Disease (IBD). If your cat has been diagnosed with B cell (large cell) GI lymphoma or T cell (small cell) lymphoma, their sample can really make a difference in the development of better diagnostic tools for this disease.
Inclusion Criteria:Diagnosis of Gastrointestinal Lymphoma by veterinarian and previously not vaccinated for Feline Leukemia Virus
Exclusion Criteria:Unrelated hyperthyroidism, intestinal neoplasia, adverse food reactions, renal and hepatic insufficiency, EPI, intestinal parasitism, enteropathy
Feline atopic dermatitis (also known as feline atopy or non-flea non-food allergic dermatitis) comes second only to flea allergy dermatitis as the most prevalent allergy in cats. Some estimates claim this disease affects 12.5% of the domestic cat population. Help us understand the biology behind this highly prevalent disease by enrolling your cat diagnosed with AD in this study.
Diagnosis of atopic dermatitis by a veterinarian and/or veterinary dermatologist.
Unrelated ophthalmic, respiratory, dermatological conditions including flea bite hypersensitivity, adverse food reaction, sarcoptic mange, pyoderma, yeast infection, contact dermatitis.
Food Allergic Dermatitis
This condition often presents with year-round skin inflammation and itching-related discomfort. Has your cat been diagnosed with food allergic dermatitis? Unfortunately, this is an increasingly common problem for cats. Become part of our study to help us understand the genetics and microbiome changes associated with food allergies in cats.
Diagnosis of food allergic dermatitis by a veterinarian and/or veterinary dermatologist.
Unrelated ophthalmic, respiratory, dermatological conditions including flea bite hypersensitivity, atopic dermatitis, sarcoptic mange, pyoderma, yeast infection, contact dermatitis, superficial bacterial folliculitis, Malassezia dermatitis, otitis externa and media.
Type II Diabetes mellitus is the predominant form of diabetes among cats. Between 0.5% and 2% of all cats have Diabetes mellitus. We are in active collaboration with the animal pharmaceutical company Anivive to uncover any potential genetic markers associated with an increased risk of developing diabetes. Such markers can be used for developing new diagnostic tools and therapeutics.
Diagnosis of Diabetes Mellitus by a veterinarian.
Renal glycosuria, stress hyperglycemia, unrelated pancreatitis, hyperadrenocorticism, or acromegaly, currently on medications such as glucocorticoids or progestogens.
Inflammatory Bowel Disease (IBD)
Inflammatory Bowel Disease (IBD) can affect any part of the gastrointestinal tract, but, most often, it impacts the stomach and the intestines. Chronic vomiting and diarrhea are a cause of suffering for many cats with IBD. We are looking to uncover genetic and microbiome factors associated with increased risk of developing IBD. If your cat has been diagnosed with IBD, especially the idiopathic form, we would love to work with you. Veterinary practices with a high prevalence of IBD feline patients would also be a perfect partner for us.
Diagnosis of IBD by a veterinarian.
Unrelated hyperthyroidism, intestinal neoplasia, adverse food reactions, viral infections (FeLV, FIV), renal and hepatic insufficiency, EPI, intestinal parasitism, enteropathy.
Nutrigenomics and disease
In recent years, research has shown that people have genetically or environmentally conferred differences in their metabolic rate and metabolic efficiency. While this is a relatively new field, we have strong reasons to believe that the same applies to pets. We are collaborating with the pet food company Purina Nestlé to discover novel feline genetic markers associated with metabolic rate and body condition, as well as feline diseases with high unmet need. The findings of this collaboration will help efforts in pet food personalization.
- Hypertrophic Cardiomyopathy
- Idiopathic Cystitis
- Oxalate urolithiasis
- Struvite Urolithiasis
We have an ever-growing catalog of feline genomic and oral microbiome data across different phenotypes and disease states. Industry collaborators can leverage this wealth of anonymized, aggregated information for the purpose of identifying novel disease markers and targets for the development of therapeutics and companion diagnostics, among other potential applications (including personalized nutrition).
By leveraging our extensive network, we can notify veterinarians and cat parents of relevant clinical trials and accelerate trial recruitment.
To maximize successful clinical trial outcomes, we can segment heterogeneous clinical trial patient populations into discrete groups organized by genotype, phenotype or oral microbiome profiles.
We work with industry partners who need help recruiting a study cohort matching particular criteria, as well as partners who already have their desired cohort and would like to obtain more data on it (genotype, oral microbiome).
Frequently Asked Questions
Taking part will not cost you anything.
We collect multidimensional data on each cat - genotype, microbiome profile, and health history. Analyzing these data together will help us identify novel genetic and microbial disease markers and develop precision medicine tools to improve and extend the lives of cats. Your cat's data will only ever be used in an anonymized aggregated format.
Please contact us at email@example.com.
- You have the right to be given new information about the study.
- You have the right to ask questions at any time and have them answered as soon as possible.
- You have the right to withdraw your consent from research participation at any point, with or without providing a reason.
- You have the responsibility to stay informed during your participation in a study. You should ask questions about anything you do not understand or simply want to know.
This varies by study and will be covered in your Informed Consent Document.
A requirement for application will be to submit your cat's medical records that validate the medical condition being researched. You will need to request these medical records from your cat's veterinarian.
Do you have questions? Interested in learning more about
our research programs or partnerships?