Hypertrophic cardiomyopathy causes thickening of the left ventricle of the heart (left ventricular outflow tract (LVOT) obstruction.

Chronic kidney disease (CKD) is a renal disease associated with a gradual loss of kidney function over a period of several months or years.

Polycystic kidney disease in cats (PKD) is one of the most common feline genetic diseases. Persian and related cat breeds are known to be at a higher risk.