Disease overview

Rod-cone dysplasia is an early onset retinopathy characterized by the primary loss of cone function, accompanied by variable degrees of reduced rod function. Typically, loss of central vision preceeds the loss of peripheral vision. It is also suggested that photoreceptor cell development is delayed in cats with Rdy and that these cells' degeneration follows soon after their differentiation. Rdy was first described in Abyssinian cats, although other purebred and mixed-breed cats can also have the causative mutation.

Gene name

CRX

Inheritance

Autosomal dominant

Signs and symptoms

Signs of the disease can become obvious as early as 2 weeks of age. Kittens can present with dilated pupils and sluggish pupillary light reflexes and an intermittent rotatory nystagmus developed by 4 to 6 weeks of age. Funduscopic changes can be observed as early as 8 weeks of age, with the central fundus being affected before the peripheral parts.

How is it diagnosed

Rdy is diagnosed with an in-depth opthalmic exam. Your veterinarian can both diagnose and stage the disease using this tool.

Breeds at higher risk

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Citations

https://pubmed.ncbi.nlm.nih.gov/20053974/

Disclaimer

Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.