Trait overview

The tyrosinate-Related Protein 1 (TYRP1) gene, also known as the Brown gene, modifies black pigment by dilution. This dilution of black pigment can also result in a brown color in the coat, including the base of the coat. In some cases, this gene can be altered to produce a reddish coat. Red/yellow-coated dogs will have a brown nose and paw pads.

Advice for breeders

If selecting for brown, mate individuals that are EE or Ee at the E locus, as well as the homozygous recessive b in the B locus.

Gene name(s)

TYRP1

Inheritance

Brown is recessive, black is dominant.

More common in the following breeds

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Citations

https://pubmed.ncbi.nlm.nih.gov/12140685/ https://www.researchgate.net/publication/11240721_TYRP1_and_MC1R_genotypes_and_their_effects_on_coat_color_in_dogs https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=DetailsSearch&Term=403479 https://www.omia.org/OMIA001249/9615/ https://www.animalgenetics.eu/Canine/Coat_Colour/BLocus.asp