Red/yellow coat

Trait overview

Melanocortin 1 Receptor (MC1R), also known as the Extension locus, is a gene that is responsible for producing eumelanin (black) and phaeomelanin (red or yellow) pigments. There are six known variants of this gene. Both e¹ and e² are recessive, and are responsible for a red/yellow coat. This genotype has inhibited black pigment production leading to cream, yellow, and/or red coats. The e² variant is expected to be found only in Australian Cattle Dogs and results in pale, cream-colored coats.

Gene name(s)

MC1R

Inheritance

Autosomal recessive

More common in the following breeds

Irish Setter, Labrador Retriever

Citations

https://www.omia.org/OMIA001199/9615/ https://vgl.ucdavis.edu/test/mc1r-dog