Basepaws Report

The Basepaws Breed + Health Cat DNA test digital report now offers a five-star scientific evidence grading system for every genetic health and trait marker result. The genetic markers in our report represent a deep dive into the available feline genetics research, including the very latest findings.

In this post, Basepaws shares important changes to its Cat DNA Test digital report. Learn about recent updates to genetic health markers, such as for the heart condition hypertrophic cardiomyopathy, and fun information about cat coat genetics.

The breed analysis that you receive from a Basepaws Breed + Health Cat DNA test offers an exciting glimpse into your cat’s DNA story, yet much of it remains to be told. This includes a definitive story of ancestry, which is difficult to pin down for cats. In today’s post, we’d like to share some insight into why this is, and to explain the concept of genomic similarity that is at the heart of the Basepaws breed analysis.

Today, we’re decoding one of the mysteries of genetics that relates to your Basepaws DNA report of results. It's called epistasis. When epistasis occurs, the observable expression (phenotype) of a gene—such as one responsible for the color of your kitty's coat—gets modified in some way by a completely different gene that has the ability to mask, suppress, or inhibit how that coat color gene is expressed. Epistasis helps explain why sometimes you may get a “likely to have” result for a genetic trait in your cat’s Basepaws report that doesn’t quite match up with their physical appearance.

From time to time, we update the Basepaws digital report of results for our Breed + Health Cat DNA Test. Today, we’d like to take a moment to share some details about two recent changes to our report—one for a genetic health marker linked to the common cat heart condition hypertrophic cardiomyopathy, and one for a genetic trait marker associated with the Siamese colorpoint coat pattern.

Pyruvate kinase is an enzyme involved in the metabolism of red blood cells. When mutations in the PKLR gene occur, it reduces the functionality of  this enzyme and subsequently affects the ability of red blood cells to survive and function properly. Learn about pyruvate kinase deficiency in cats, symptoms and treatment, and the cat breeds that are known to be at a higher risk for this condition.

We're sharing details about an exciting improvement to the Basepaws report—one that helps us capture an even clearer picture of the colorful and unique "landscape" of your kitty's genome! Get all the details about this new update related to the genetic traits that are responsible for your cat's fabulous appearance in today's blog.

Porphyrias is a term for a group of rare metabolic disorders that affect a cat’s ability to produce heme. Heme is an essential part of hemoglobin—a protein found in red blood cells that brings oxygen from a cat’s lungs to other parts of their body. Different types of porphyrias can occur in cats, as well as in humans and other animals. In this blog, we’ll discuss acute intermittent porphyria (AIP) in cats, its symptoms, and how it is diagnosed and treated by veterinarians.