

Basepaws is excited to announce that it is adding over 80 genetic health and trait markers to its flagship at-home Breed + Health Cat DNA test. In total, the test will now screen your cat for over 120 markers and will offer features that no other direct-to-consumer (D2C) test provides.

Today, we’re decoding one of the mysteries of genetics that relates to your Basepaws DNA report of results. It's called epistasis. When epistasis occurs, the observable expression (phenotype) of a gene—such as one responsible for the color of your kitty's coat—gets modified in some way by a completely different gene that has the ability to mask, suppress, or inhibit how that coat color gene is expressed. Epistasis helps explain why sometimes you may get a “likely to have” result for a genetic trait in your cat’s Basepaws report that doesn’t quite match up with their physical appearance.

From time to time, we update the Basepaws digital report of results for our Breed + Health Cat DNA Test. Today, we’d like to take a moment to share some details about two recent changes to our report—one for a genetic health marker linked to the common cat heart condition hypertrophic cardiomyopathy, and one for a genetic trait marker associated with the Siamese colorpoint coat pattern.

Pyruvate kinase is an enzyme involved in the metabolism of red blood cells. When mutations in the PKLR gene occur, it reduces the functionality of this enzyme and subsequently affects the ability of red blood cells to survive and function properly. Learn about pyruvate kinase deficiency in cats, symptoms and treatment, and the cat breeds that are known to be at a higher risk for this condition.

We're sharing details about an exciting improvement to the Basepaws report—one that helps us capture an even clearer picture of the colorful and unique "landscape" of your kitty's genome! Get all the details about this new update related to the genetic traits that are responsible for your cat's fabulous appearance in today's blog.

Porphyrias is a term for a group of rare metabolic disorders that affect a cat’s ability to produce heme. Heme is an essential part of hemoglobin—a protein found in red blood cells that brings oxygen from a cat’s lungs to other parts of their body. Different types of porphyrias can occur in cats, as well as in humans and other animals. In this blog, we’ll discuss acute intermittent porphyria (AIP) in cats, its symptoms, and how it is diagnosed and treated by veterinarians.

We are continually adding new breeds to our database. Our Basepaws Cat DNA report currently includes the following cat breeds.

Meet Sami. This loving and adorable fellow is one of four cats that Basepaws community member, Giuliano Argenti, rescued and welcomed into his family. At the wise age of 19, Sami is living a healthy and full life—yet this wasn’t always the case. Learn about how the Basepaws Oral Health Test helped Guiliano and his veterinarian save Sami’s pearly whites, and ultimately, his life. It’s a story with a happy ending that gives us all something to smile about!