Hyperlipoproteinaemia is an autosomal recessive disorder resulting in an increased amount of lipids, or fat, in the blood. It is caused by a deficiency in the lipoprotein lipase enzyme (LPL). The persistently elevated blood levels of cholesterol and tryglicerides associated with this disease can increase the likelihood of developing cardiovascular diseases.
LPL
Likely autosomal recessive; some dosage effects in heterozygotes
Cats with this disorder may not show any signs. The most common presentations include GI disruption, abdominal pain, and seizures.
This disease is diagnosed via bloodwork. Serum triglyceride concentrations will be increased, particularly when the animal has not eaten recently. Lipid and cholesterol concentrations should be measured. Lipoprotein electrophoresis can also be done for a diagnosis.
Current data does not indicate that specific breeds are at a higher risk.
https://pubmed.ncbi.nlm.nih.gov/8636438/
Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.
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