Disease overview

Copper is instrumental in various metabolic processes. This element is absorbed from the small intestine and processed in the liver. Wilson's disease is characterized by impaired copper secretion to bile and blood, leading to copper accumulation in the liver, as well as other tissues such as the brain, kidney and cornea. Increased amounts of copper cause oxidative stress and cell death.

Gene name

ATP7B

Inheritance

Autosomal recessive

Signs and symptoms

Clinical signs of Wilson's disease can vary depending on where the copper accumulates. In some cases, cats will present with jaundice, lethargy, and inappetance.

How is it diagnosed

A diagnosis is made after detecting high levels of copper in the blood or different body systems such as the liver.

Breeds at higher risk

Current data does not indicate that specific breeds are at a higher risk.

Citations

https://pubmed.ncbi.nlm.nih.gov/30561139/ https://pubmed.ncbi.nlm.nih.gov/31687873/

Disclaimer

Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.