Oculoskeletal dysplasia 2 is a skeletal disease that causes dwarfism, lameness, and vision loss. It is caused by a defect in collagen.
COL9A2
Autosomal recessive
Early onset of clinical signs appear around 4-6 weeks of age. They include short limbs and an enlarged skull. Eye changes (often to green) may occur, and/or hyperreflectivity of the eye accompanied by vision loss. Dogs may present with lameness and early-onset arthritis.
Thorough examination of the eyes and clinical signs. A veterinary ophthalmologic exam can determine if there are changes in the eye that have or will lead to vision loss. Genetic testing is necessary to determine if there is an underlying genetic cause, which can assist veterinarians with diagnosis and help breeders identify affected and carrier dogs.
Meyers VN, Jezyk PF, Aguirre GD, Patterson DF. Short-limbed dwarfism and ocular defects in the Samoyed dog. J Am Vet Med Assoc. 1983 Nov 1;183(9):975-9. PMID: 12002589.
Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.
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