Trait overview

A missense variant in the gene MFSD12 leads to a dilution of the red pigment called phaeomelanin. This leads to a white or cream coat in dogs.

Gene name(s)

MFSD12

Inheritance

Autosomal recessive

More common in the following breeds

West Highland White Terrier, , ,

Citations

https://pubmed.ncbi.nlm.nih.gov/31117290/ https://www.omia.org/OMIA002197/9615/ https://doi.org/10.1111/age.13154