Agouti Signaling Protein (ASIP) gene interacts with the MC1R gene. This interaction controls pigment-switching in dogs between red pigment (phaeomelanin) and black pigment (eumelanin) and affects the type of pigments that occur in a dog, their amount, and their distribution in a dog's coat.
ASIP
Multifactorial
https://pubmed.ncbi.nlm.nih.gov/15965787/ https://vgl.ucdavis.edu/test/agouti-dog https://doi.org/10.1111/age.13154
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