Today, we’re decoding one of the mysteries of genetics that relates to your Basepaws DNA report of results. It's called epistasis. When epistasis occurs, the observable expression (phenotype) of a gene—such as one responsible for the color of your kitty's coat—gets modified in some way by a completely different gene that has the ability to mask, suppress, or inhibit how that coat color gene is expressed. Epistasis helps explain why sometimes you may get a “likely to have” result for a genetic trait in your cat’s Basepaws report that doesn’t quite match up with their physical appearance.
From time to time, we update the Basepaws digital report of results for our Breed + Health Cat DNA Test. Today, we’d like to take a moment to share some details about two recent changes to our report—one for a genetic health marker linked to the common cat heart condition hypertrophic cardiomyopathy, and one for a genetic trait marker associated with the Siamese colorpoint coat pattern.
The breed analysis that you receive from a Basepaws Breed + Health Cat DNA test offers an exciting glimpse into your cat’s DNA story, yet much of it remains to be told. This includes a definitive story of ancestry, which is difficult to pin down for cats. In today’s post, we’d like to share some insight into why this is, and to explain the concept of genomic similarity that is at the heart of the Basepaws breed analysis.
Our cat's DNA make-up matters. All the information required for the functioning of every little bit of your cat's body is written in the genes. Luckily, with Basepaws, discovering your cat's genetic background, ancestry and health predispositions have now become a lot easier and less expensive than ever.