Disease overview

Congenital hypogonadotropic hypogonadism (HH) is a rare genetic disorder that results in incomplete puberty. This is due to an inability to secrete the proper amounts of gonadotropic-releasing hormone (GnRH), despite having an otherwise normal hypothalamus and pituitary gland.

Gene name

TAC3

Inheritance

Autosomal recessive

Signs and symptoms

Clinical signs of HH include infertility, cryptorchidism (where the testicles do not descend into the scrotum), and a micropenis.

How is it diagnosed

The diagnosis of HH is made based on clinical signs and history. It is confirmed by measuring the levels of testosterone and pituitary hormones in the blood.

Breeds at higher risk

Current data does not indicate that specific breeds are at a higher risk.

Citations

https://pubmed.ncbi.nlm.nih.gov/31615056/

Disclaimer

Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.