Sensory ataxic neuropathy is an inherited neurological condition that causes degeneration of the nerves in the body. It is characterized by uncontrolled muscle movement, abnormal posture, and decreased spinal reflex.
tRNA-Tyr (MT-TY)
Mitochondrial
Clinical signs are early-onset when an affected dog is a puppy. These include difficulty walking, a hard time maintaining normal posture, and abnormal, uncoordinated movements (ataxia).
A veterinarian will conduct a thorough exam, including a review of health history and any clinical signs. Neurological tests, including imaging, may be required for a definitive diagnosis. Genetic testing is necessary to determine if there is an underlying genetic cause, which can assist veterinarians with diagnosis and help breeders identify affected and carrier dogs.
, Golden Doodle
Baranowska I, JĂ€derlund KH, Nennesmo I, Holmqvist E, Heidrich N, Larsson NG, Andersson G, Wagner EG, Hedhammar A, Wibom R, Andersson L. Sensory ataxic neuropathy in golden retriever dogs is caused by a deletion in the mitochondrial tRNATyr gene. PLoS Genet. 2009 May;5(5):e1000499. doi: 10.1371/journal.pgen.1000499. Epub 2009 May 29. PMID: 19492087; PMCID: PMC2683749.
Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.
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