Disease overview

Pancreatitis is a term that refers to inflammation of the pancreas. The pancreas is an important organ in the process of food digestion and regulation of byproducts through the release of hormones. This is a fairly common condition that can have a variety of causes, including genetic causes.

Gene name

SPINK1

Inheritance

Autosomal recessive

Signs and symptoms

Dogs suffering from pancreatitis may present with vomiting, nausea, fever, lethargy, diarrhea, decreased appetite, and abdominal pain (the latter may be indicated by a hunched back).

How is it diagnosed

A veterinarian will conduct a thorough exam, including a review of health history and any clinical signs. Laboratory testing can check the function of the pancreas. Imaging may be used. Genetic testing is necessary to determine if there is an underlying genetic cause, which can assist veterinarians with diagnosis and help breeders identify affected and carrier dogs.

Breeds at higher risk

Citations

Bishop MA, Xenoulis PG, Levinski MD, Suchodolski JS, Steiner JM. Identification of variants of the SPINK1 gene and their association with pancreatitis in Miniature Schnauzers. Am J Vet Res. 2010 May;71(5):527-33. doi: 10.2460/ajvr.71.5.527. PMID: 20433378.

Disclaimer

Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.