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Mutations in melanophilin (MLPH) causes dilution base coat colors, such as black and red pigments. These dilutions often lead to a gray-blue or pale silvery red color, depending on the base color. There are three variants of this gene that play a role in color dilution. Two copies of any three variants, or a combination of two variants, are necessary to cause a dilution of color.
MLPH
Autosomal recessive
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https://pubmed.ncbi.nlm.nih.gov/17519392/ https://www.omia.org/OMIA000031/9615/ https://vgl.ucdavis.edu/test/dilute-dog https://doi.org/10.1111/age.13154
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