Disease overview

The Growth Differentiation Factor 9 (GDF9) gene is known to regulate oocyte maturation. A variant in this gene is associated with smaller litter sizes.

Gene name

GDF9

Inheritance

Complex

Signs and symptoms

NA

How is it diagnosed

NA

Breeds at higher risk

Citations

Torrecilha RBP, Milanesi M, Wade CM, Gallana M, Falbo AK, Reichler IM, Hug P, Jagannathan V, Trigo BB, Paulan SC, Bruno DB, Garcia SD, Scaramele NF, Lopes FL, Dolf G, Leeb T, Sölkner J, Garcia JF, Pieńkowska-Schelling A, Schelling C, Utsunomiya YT. Association of missense variants in GDF9 with litter size in Entlebucher Mountain dogs. Anim Genet. 2020 Feb;51(1):78-86. doi: 10.1111/age.12882. Epub 2019 Dec 4. Erratum in: Anim Genet. 2020 Jun;51(3):488. PMID: 31802524.

Disclaimer

Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.