Factor XI deficiency

Disease overview

Factor XI deficiency is a secondary hemostatic disease that leads to failure of platelet plug stabilization during the coagulation/clotting pathway.

Gene name

F11

Inheritance

Autosomal recessive

Signs and symptoms

Factor XI deficiency can present with mild bleeding. Clotting conditions are typically recognized during trauma or preparation for surgery.

How is it diagnosed

Secondary hemostatic diseases are diagnosed with a range of blood tests that determine blood clotting times.

Breeds at higher risk

Kerry Blue Terrier

Citations

Knowler C, Giger U, Dodds WJ, Brooks M. Factor XI deficiency in Kerry Blue Terriers. J Am Vet Med Assoc. 1994 Dec 1;205(11):1557-61. PMID: 7730123.

Disclaimer

Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.