Disease overview

Afibrinogenaemia is a blood disorder in which the blood component, fibrinogen, is lacking. Fibrinogen is used in the clotting and coagulation cascade during injury.

Gene name

FGA

Inheritance

Autosomal recessive

Signs and symptoms

Affected dogs can show signs of increased bleeding tendency. Clotting conditions are typically recognized during trauma or in preparation for surgery.

How is it diagnosed

Hemostatic diseases are diagnosed with multiple blood tests that evaluate clotting times. Fibrinogen can be measured in the blood.

Breeds at higher risk

Miniature Wirehaired Dachshund

Citations

Mischke R, Metzger J, Distl O. An FGA Frameshift Variant Associated with Afibrinogenemia in Dachshunds. Genes (Basel). 2021 Jul 13;12(7):1065. doi: 10.3390/genes12071065. PMID: 34356081; PMCID: PMC8304930.

Disclaimer

Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.