Disease overview

May-Hegglin Anomaly is a blood condition. This is a benign disease of the platelets that is characterized by abnormally large platelets that are low in number.

Gene name

MYH9

Inheritance

Autosomal dominant

Signs and symptoms

This disease does not typically present with clinical signs. There may be an increased risk of bleeding and bruising.

How is it diagnosed

A veterinarian will conduct a thorough exam, including a review of health history. A complete blood count (CBC) test that measures many different parts and features of the blood may show platelet abnormalities. Genetic testing is necessary to determine if there is an underlying genetic cause, which can assist veterinarians with diagnosis and help breeders identify affected and carrier dogs.

Breeds at higher risk

Citations

Flatland B, Fry MM, Baek SJ, Bahn JH, LeBlanc CJ, Dunlap JR, Carroll RC, Kosiba DJ, Millsaps DJ, Schleis SE. May-Hegglin anomaly in a dog. Vet Clin Pathol. 2011 Jun;40(2):207-14. doi: 10.1111/j.1939-165X.2011.00320.x. Epub 2011 May 9. PMID: 21554370.

Disclaimer

Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.