Disease overview

Prekallikrein deficiency is a blood condition in which affected dogs have long clotting times, but not an increased bleeding risk. Prekallikrein is involved in the early stages of blood clot formation.

Gene name

KLKB1

Inheritance

Autosomal recessive

Signs and symptoms

Affected dogs have prolonged clotting times, but do not have increased bleeding risk.

How is it diagnosed

Hemostatic diseases are diagnosed with multiple blood tests that evaluate clotting times.

Breeds at higher risk

Citations

Okawa T, Yanase T, Shimokawa Miyama T, Hiraoka H, Baba K, Tani K, Okuda M, Mizuno T. Prekallikrein deficiency in a dog. J Vet Med Sci. 2011 Jan;73(1):107-11. doi: 10.1292/jvms.10-0207. Epub 2010 Aug 23. PMID: 20736516.

Disclaimer

Disease diagnosis and treatment should always be performed by a veterinarian. The following information is for educational purposes only.